Epilepsy - Treatment & Services

The Comprehensive Epilepsy Center at Temple Neurosciences at Boyer Pavilion is one of the premier facilities in the region for evaluating and treating patients with all forms of epilepsy and seizure disorders. A highly skilled, multidisciplinary medical team that includes neurologists, neurosurgeons, nurse coordinators and rehabilitation specialists offers a complete range of diagnostic and treatment options designed to provide patients from teens to adulthood with the highest standard of care.

Comprehensive, state-of-the-art diagnostic services are available to classify seizures, clarify diagnosis and optimize treatment. These include:

  •  Electroencephalography (EEG). Both continuous and long-term monitoring are available. For patients with intractable recurrent seizures or an unconfirmed seizure diagnosis, video-EEG monitoring can provide further information
  •  3.0 Tesla MRI (Magnetic Resonance Imaging)
  • Functional MRI (fMRI)

Treatment Options

Temple’s Comprehensive Epilepsy Center offers a wide variety of treatment options, including:

  • State-of-the-art investigational drug therapy (AEDs)
  • Neurosurgical evaluation and treatment. Surgery has the potential to relieve seizure activity in more than 80% of patients with temporal lobe epilepsy. The majority of those who are seizure-free for the first year after surgery have a favorable long-term outcome
  • Deep brain stimulation (DBS) and Vagus Nerve Stimulation are associated with reduction in seizures for individuals with retractable epilepsy
  • Extratemporal cortical resection may be performed for individuals with intractable epilepsy

Other procedures include:

  • Temporal lobe resections
  • Focal non-temporal resections
  • Corpus callosotomy 
  • Lesionectomy

Co-morbidity Management

Patients with heart conditions, HIV or the elderly may be using medications that can interact with anti-seizure medications. Temple neurologists will review efficacy and tolerance for appropriate usage based on co-morbidity of conditions that may be present in these patients

Areas of Interest:

Special populations with epilepsy, including stroke survivors:

  • High-risk obstetrics for women with epilepsy. Temple physicians provide pre-conception counseling, genetic counseling and coordination of care. Patients are accepted who do not plan a delivery at Temple
  • Older adults with epilepsy. Epilepsy may occur with Alzheimer’s disease or following a stroke (CVA). Elderly patients may be more sensitive to anti-seizure medications. Drug interactions are more likely to occur
  • The effects of AEDs on bone health. Temple neurologists recommend a DEXA (Dual Energy X-ray Absorbimetry) scan to detect osteopenic or osteoporotic bones weakened by anti-epileptic medications
  • The psychological effects of AEDs
  • Epilepsy self-efficacy
  • New protocols for treating epilepsy. The Department actively recruits patients for clinical trials. In some cases, patients benefit from no-cost MRIs and EEGs.

For information about current trials for patients with seizure disorders, call the clinical research coordinator at 215-707-7845.